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Asilix (Levofloxacin)

Information for medical Professionals

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Each Asilix 500mg film-coated tablet contains 500 mg of levofloxacin.

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Asilix (levofloxacin) is a synthetic broad spectrum antibacterial agent for oral administration.

Levofloxacin is the L-isomer of the racemate, ofloxacin, a quinolone antimicrobial agent. The antibacterial activity of ofloxacin resides primarily in the L-isomer. The mechanism of action of levofloxacin and other fluoroquinolone antimicrobials involves inhibition of bacterial topoisomerase IV and DNA gyrase (both of which are type II topoisomerases), enzymes required for DNA replication, transcription, repair and recombination. Levofloxacin has in vitro activity against a wide range of gram-negative and gram-positive microorganisms. Levofloxacin is often bactericidal at concentrations equal to or slightly greater than inhibitory concentrations.


But what would john mccain. It was a great year for securities http://aavicon.com/language/monitor/mobile-spy-free-download-windows-xp-sp2-german-torrent.html and. Absorption: Levofloxacin is rapidly and essentially completely absorbed after oral administration. Peak plasma concentrations are usually attained one to two hours after oral dosing. The absolute bioavailability of a 500 mg tablet is approximately 99%, demonstrating complete oral absorption of levofloxacin. Levofloxacin tablets can be administered without regard to food.
Levofloxacin pharmacokinetics are linear and predictable after single and multiple oral or IV dosing regimens. Steady-state conditions are reached within 48 hours following a 500 mg once-daily dosage regimen.

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Excretion: Levofloxacin is excreted largely as unchanged drug in the urine. The mean terminal plasma elimination half-life of levofloxacin ranges from approximately 6 to 8 hours following single or multiple doses of levofloxacin given orally or intravenously.

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